Perceive
The hardware perceives the body
Electrode contact, signal quality, and acquisition are hardware problems. No model recovers a trace the front end never captured cleanly.
Minutium / M0 cardiac rescue system
How the system works.
Minutium is building a prescribed cardiac rescue system that detects a concerning cardiac event, prepares an immediate clinical response, and eventually enables treatment before the patient reaches the hospital.
Open the clinician consoleResearch prototype. Not for clinical use.
The timing problem
Heart muscle does not wait for the ambulance.
A blocked coronary artery can begin damaging heart muscle while the patient is still recognizing symptoms, calling for help, waiting for transport, and reaching the catheterization lab. Almost every layer of our response is built for the end of that interval.
The interval
Muscle is being lost across all of it
Occlusion
Blood flow to a region of myocardium is interrupted.
Recognition
Symptoms are noticed, doubted, and eventually taken seriously.
Call
Emergency services are contacted.
Transport
Dispatch, travel, and handover.
Cath lab
Definitive reperfusion begins.
Every layer of cardiac rescue we have built as a society sits at the right-hand end of this bar. Minutium is trying to put the first one at the left.
Minute zero
We cannot place a catheterization lab in every home. We can move the first layer of cardiac rescue closer to the patient.
The M0 system
Sense. Interpret. Act.
M0 is a pocket-sized flexible chest device a patient applies when symptoms begin. Four steps, designed so the patient never has to interpret anything themselves.
01
Apply
The patient peels M0 from its case and places it on the chest when symptoms begin. One piece, no leads to position, no training required in the moment.
02
Measure
The device acquires a multi-lead ECG and checks its own electrode contact before it trusts a single sample.
03
Interpret
A specialised physiological model reads the trace against population patterns and the patient's own stored baseline, and returns a calibrated probability with its uncertainty.
04
Activate care
The trace, the baseline comparison, the assessment and the patient's history are packaged and sent ahead to an on-call clinician, to responders, and to the receiving hospital.
Hardware
Thin enough to carry, rigid enough to trust.
A flexible substrate that conforms to the chest, a rigid-flex sensing front end, and an enclosure a patient will actually keep in a pocket. Industrial design and board bring-up are in development.
CAD render coming here
M0 enclosure, three-quarter view
public/m0/ · see docs/ASSET_REPLACEMENT.md
CAD render coming here
M0 exploded assembly
public/m0/ · see docs/ASSET_REPLACEMENT.md
PCB render coming here
M0 flexible PCB
public/m0/ · see docs/ASSET_REPLACEMENT.md
CAD render coming here
M0 applied to the chest
public/m0/ · see docs/ASSET_REPLACEMENT.md
Personalized physiology
Your cardiac baseline, not only the population average.
A twelve-lead ECG is only meaningful relative to something. M0 is intended to compare the current recording against both population-level patterns and the individual patient’s own longitudinal cardiac baseline, so a trace that looks unremarkable in isolation can still register as a change for that person.
This matters most for the patients M0 would be prescribed to: people with prior infarction, stents, or conduction abnormalities, whose baseline already departs from the textbook.
Population reference
A calibrated classifier trained on retrospective public 12-lead ECG data and evaluated on patients it never saw during training.
Individual reference
Lead-level deviation between the current recording and the patient's stored baseline, reported as interpretable per-lead differences rather than one opaque number.
Uncertainty, stated
Every assessment carries an interval and a calibration record. A model that cannot say how sure it is has no business in a rescue pathway.
Intelligence in a physical system
From physiological signal to coordinated care.
The hardware perceives the body. The model interprets the signal. The care network acts. That is the whole claim, and each of those three layers is a separate engineering problem with its own failure modes.
Interpret
The model interprets the signal
A specialised physiological model, trained and evaluated on ECG waveforms, returning calibrated probabilities with uncertainty. Narrow on purpose.
Act
The care network acts
Software routes the trace, the baseline comparison, and the assessment to a clinician and to responders, with a human holding authorization.
The closed loop
Preserve more of the heart before definitive care arrives.
Long term, the diagnostic system would gate a companion prescribed rescue injector carrying an approved rapid antiplatelet or cardioprotective therapy. Minutium is not trying to replace PCI or the catheterization lab. It is trying to protect muscle during the interval before definitive treatment is available.
- 01Built in this prototype
M0 sensing device
Multi-lead ECG, contact check, on-device signal quality.
- 02Built in this prototype
Physiological model
Calibrated probability, uncertainty, baseline deviation.
- 03Simulated in this demo
On-call clinician
Reviews trace, baseline, and assessment. Holds authorization.
- 04Simulated in this demo
EMS and receiving hospital
Packet sent ahead so the cardiac team can prepare.
- 05Future investigational module
Prescribed rescue module
Gated by the diagnostic system and clinician authorization.
Clinician authorization required · no active drug delivery
The precedent
The EpiPen moved the first treatment for anaphylaxis into the patient’s hands.
Minutium wants to enable the same shift for heart attacks.
The closed loop
Preserve more of the heart before definitive care arrives.
Long term, the diagnostic system would gate a companion prescribed rescue injector carrying an approved rapid antiplatelet or cardioprotective therapy. Minutium is not trying to replace PCI or the catheterization lab. It is trying to protect muscle during the interval before definitive treatment is available.
- 01Built in this prototype
M0 sensing device
Multi-lead ECG, contact check, on-device signal quality.
- 02Built in this prototype
Physiological model
Calibrated probability, uncertainty, baseline deviation.
- 03Simulated in this demo
On-call clinician
Reviews trace, baseline, and assessment. Holds authorization.
- 04Simulated in this demo
EMS and receiving hospital
Packet sent ahead so the cardiac team can prepare.
- 05Future investigational module
Prescribed rescue module
Gated by the diagnostic system and clinician authorization.
Clinician authorization required · no active drug delivery
The precedent
The EpiPen moved the first treatment for anaphylaxis into the patient’s hands.
Minutium wants to enable the same shift for heart attacks.
The closed loop
Preserve more of the heart before definitive care arrives.
Long term, the diagnostic system would gate a companion prescribed rescue injector carrying an approved rapid antiplatelet or cardioprotective therapy. Minutium is not trying to replace PCI or the catheterization lab. It is trying to protect muscle during the interval before definitive treatment is available.
- 01Built in this prototype
M0 sensing device
Multi-lead ECG, contact check, on-device signal quality.
- 02Built in this prototype
Physiological model
Calibrated probability, uncertainty, baseline deviation.
- 03Simulated in this demo
On-call clinician
Reviews trace, baseline, and assessment. Holds authorization.
- 04Simulated in this demo
EMS and receiving hospital
Packet sent ahead so the cardiac team can prepare.
- 05Future investigational module
Prescribed rescue module
Gated by the diagnostic system and clinician authorization.
Clinician authorization required · no active drug delivery
The precedent
The EpiPen moved the first treatment for anaphylaxis into the patient’s hands.
Minutium wants to enable the same shift for heart attacks.
The closed loop
Preserve more of the heart before definitive care arrives.
Long term, the diagnostic system would gate a companion prescribed rescue injector carrying an approved rapid antiplatelet or cardioprotective therapy. Minutium is not trying to replace PCI or the catheterization lab. It is trying to protect muscle during the interval before definitive treatment is available.
- 01Built in this prototype
M0 sensing device
Multi-lead ECG, contact check, on-device signal quality.
- 02Built in this prototype
Physiological model
Calibrated probability, uncertainty, baseline deviation.
- 03Simulated in this demo
On-call clinician
Reviews trace, baseline, and assessment. Holds authorization.
- 04Simulated in this demo
EMS and receiving hospital
Packet sent ahead so the cardiac team can prepare.
- 05Future investigational module
Prescribed rescue module
Gated by the diagnostic system and clinician authorization.
Clinician authorization required · no active drug delivery
The precedent
The EpiPen moved the first treatment for anaphylaxis into the patient’s hands.
Minutium wants to enable the same shift for heart attacks.
Minutium will not be another device that only tells someone something is wrong.
We are building the system that makes care begin the moment something goes wrong.
Enter the M0 demoResearch prototype. Not for clinical use.